I've always felt strongest about Spider-Man as a superhero because there's a certain weight to his mythos. Someone that is perpetually isolated from the public, his friends, and family, yet never gives up or loses sight of the bigger picture.
To think how tortured of a soul he would have to be, likely burying his head in his work to avoid letting the thought of it sink him down. One can only imagine it unavoidable at times...many times. I wanted to convey that here.